Karine Deshayes (Poppea); Jeremy Ovenden (Nerone); Andrea Concetti (Seneca); Varduhi Abrahamyan (Ottone); Monica Bacelli (Ottavia); Gaëlle Arquez (La Fortuna/Drusilla); Jael Azzaretti (La Virtù/Damigella); Amel Brahim-Djelloul (Amore); Manuel Nunes Camelino (Arnalta); Giuseppe de Vittorio Nutrice
Monteverdi's opera is in three acts, all set in ancient Rome, in the year 65 A.D. The main characters include Nero, the Roman emperor; Poppea, his lover; Otho, Poppea's fiancé; Drusilla, who is in love with Otho; and Octavia, Nero's wife.
As ACT ONE begins we meet Otho, returning from a long journey. When he arrives home, he finds some of Nero's soldiers hanging around -- and he knows what that means. Nero is inside, romancing Poppea. As the lovers emerge, Poppea makes Nero promise to get rid of his wife, Octavia, and crown Poppea as empress.
Meanwhile, Octavia knows exactly what Nero is up to with Poppea. Seneca, an elder statesman, tries to console her. Then, when Nero confirms his intentions to dump his wife and stay with Poppea, the highly moral Seneca objects. Nero angrily dismisses him, and Poppea convinces Nero that they it would be best if Seneca were out of the picture for good.
Otho overhears all this, and appeals to Poppea to give their relationship another chance. She tells him it's hopeless. What would she want with him, when she can be with the emperor instead? When she leaves, Otho considers murdering her. He also decides that maybe he'd be better off with a woman who really loves him -- Drusilla, for example. When he goes to her, she's suspicious, but eventually welcomes him. Still, Otho can't shake his love for Poppea.
ACT TWO begins in a Seneca's garden. At Poppea's urging, Nero has ordered Seneca's death, and Seneca has decided to carry out that order himself. One of his servants brings him a knife, and Seneca asks a few friends to witness his suicide. When Nero finds out what Seneca has done he's ecstatic, and reacts with a highly-charged scene praising Poppea's sensuous beauty.
Despite Nero's betrayal, Octavia still hasn't given up on saving their marriage. And if that's going to happen, she concludes, Poppea will have to be killed. But Octavia won't be doing that herself. Instead, she orders Otho to commit the crime. He turns to the faithful Drusilla for help, and she lends him her clothes, for a disguise.
Poppea, not realizing the danger she's in, prays to Cupid to ensure her marriage to Nero. That turns out to be a good move. Later on, Otho quietly enters Poppea's room with his dagger in hand, but Cupid intervenes and prevents the murder. Poppea wakes up just as the disguised Otho is running away. She mistakes him for Drusilla and, naturally, tells everyone that Drusilla has just tried to kill her.
At the start of ACT THREE Drusilla has been arrested, and she decides to accept her fate. She wasn't the one with the dagger in hand, but she was an essential part of the plan, she admits her guilt. She also goes one step further. In spite of everything, she's still in love with Otho. So, when she's brought before Nero for judgment, she says it really was her that Poppea saw that night -- and that Otho had nothing to do with it. Nero promptly orders her execution.
That's too much for Otho, who isn't completely without scruples. He steps forward and confesses. But he decides not to go down alone, and also reveals Octavia's role as instigator of the plot. That gives Nero just the opening he needs -- a perfect excuse to get rid of Octavia. He orders up a boat and has her shipped off into exile.
Nero then decides to spare Otho from a death sentence. Instead, he exiles him, as well. But at least Otho won't have to slink off alone -- Nero says Otho can take Drusilla with him.
With all the sentences passed, Nero and Poppea arrange to be married, and Octavia sings a famous and beautiful farewell to her home -- "Addio Roma."
The final scene takes place at Nero's palace. Nero and Poppea confirm their love, and Poppea is crowned Empress. After the coronation, the opera ends with its best-known music, a quietly passionate duet for the newlyweds.